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Tirzepatide

Important disclaimer

This page is for educational purposes only. Always consult a licensed doctor, get baseline + follow-up blood work, and use entirely at your own risk.


In simple terms

Tirzepatide is a dual GLP-1 + GIP peptide.
It mimics two gut hormones at once → you feel full very quickly, cravings disappear, and your body burns fat faster than with semaglutide alone.

Average results from real users and clinical trials:

  • 15–18 % body weight in 48 weeks
  • 20–22 % in 72 weeks

Golden rule: Only increase the dose when the day your appetite starts coming back

Stay on the lowest dose that keeps you full and losing 0.5–1 kg per week.
There is no rush to go up. Many people stay on 5 mg or 7.5 mg forever and keep losing.

Week Suggested Dose Rule of Thumb
1–4 2.5 mg Mandatory starting dose
5+ 5.0 mg Move up only if hunger returns
9+ 7.5 mg Move up only if hunger returns
13+ 10 mg Move up only if hunger returns
21+ 12.5 or 15 mg Only for very large individuals or true plateau

Expected Timeline

Time What happens
Week 1–2 Appetite drops 30–50 %, mild nausea possible
Week 3–6 Noticeably looser clothes, energy improves
Month 2–3 8–15 kg down, face slims
Month 6–12 20–35+ kg total loss is very common

Side Effects & How to Handle Them

Most side effects are mild and disappear after 4–6 weeks

  • Nausea (worst days 1–2 after injection) → take at night + eat small bland meals
  • Constipation → drink 3 L water + eat vegetables/fiber
  • Sulfur burps → avoid oily food the day of injection
  • Fatigue → normal while body adjusts to lower calories

Blood Work You Should Get

Test When Approx Cost (Hi-Precision)
CBC + Fasting Glucose + HbA1c Baseline & every 3 months ₱1200–1800
Lipid panel Baseline & every 6 months ₱800–1200
TSH + Free T4 Baseline & every 6 months ₱1000–1500
ALT/AST (liver) Baseline & every 3 months ₱500–800

Bottom line

Tirzepatide is currently the strongest and most tolerable weight-loss peptide available in research form.
Stay on the lowest effective dose → maximum results with minimum side effects.

Ready to start?

You’ve got this!