GHK-Cu (Injectable)¶

Tags: GHK-Cu, Copper Peptide, Skin Regeneration, Injectable

Quick Facts¶

• Typical Dose: 1–3 mg (1–2× daily)
• Route: Injectable — SubQ (belly, thigh, arm)
• Cycle: 8–12 weeks (typical)
• Storage: 2–8°C (refrigerated)

Overview¶

GHK‑Cu is a naturally occurring copper tripeptide found in human plasma, saliva, and urine. Plasma levels decline from ~200 ng/ml at age 20 to ~80 ng/ml by age 60. Research shows it affects a large portion of human gene expression and promotes wound healing, collagen synthesis, and anti‑aging effects. Injectable GHK‑Cu provides systemic bioavailability but is not FDA‑approved; most high‑quality clinical evidence is from topical studies and animal models.

Key Benefits¶

• Maximum bioavailability and systemic anti‑aging effects
• Enhanced collagen production and deep dermal remodeling
• Accelerated wound healing and improved angiogenesis
• Hair growth stimulation

Mechanism of action¶

Injectable GHK‑Cu activates multiple cellular pathways including collagen synthesis, angiogenesis, immune modulation, and tissue remodeling genes that support comprehensive anti‑aging effects.

Molecular information¶

• Weight: 404.96 Da
• Length: 3 amino acids
• Type: Copper tripeptide

Amino Acid Sequence:

Gly-His-Lys

Complexed with copper (Cu2+) for enhanced bioavailability.

Research indications¶

• Anti‑inflammatory
• Skin regeneration
• Hair growth stimulation
• Wound healing

Research protocols¶

Timing: Injectable GHK‑Cu is usually administered subcutaneously. Rotate sites to prevent irritation. Consistent timing supports steady levels.

Interactions¶

How to reconstitute¶

1. Allow vial to reach room temperature (15–20 minutes).
2. Clean vial tops and injection sites with alcohol swabs.
3. Draw calculated amount of bacteriostatic water (BAC) into syringe.
4. Inject slowly down the vial side to avoid direct contact with powder.
5. Gently swirl until fully dissolved (characteristic light blue color).
6. Store reconstituted solution in refrigerator at 2–8°C and use within 30 days.

Important: Always use bacteriostatic water (BAC) and sterile technique.

Quality Indicators¶

Side effects & safety¶

• Monitor injection sites for unusual blue discoloration
• Start with lower doses to assess copper tolerance
• Use sterile injection technique to prevent infection
• Watch for signs of copper toxicity (nausea, metallic taste)
• Avoid excessive copper supplementation from other sources

References¶